GO:0007252 biological_process I-kappaB phosphorylation
| PAG Title | GO:0007252 biological_process I-kappaB phosphorylation |
| PAG ID | TAX016866 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 1,107 |
| Information Content | Rich |
| Other IDs | GO:0007252 |
| Base PAG ID | TAX016866 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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